The History & Uses of Botox, Dysport & Xeomin
Article tagsHealth Med Spa Services
Today we have more choices than ever when looking to correct dynamically caused lines & wrinkles. Along with Botox, we now have two additional FDA approved options in Dysport and Xeomin. At [mrktmade_shortcode config=”practice”], we specialize in providing patients “Natural Look Aesthetics”. Over 93% of our patients who routinely receive Botox injections tell us they don’t want an unnatural look or their friends to ask “My God, what have you done”. You want to look younger & more attractive yes, but not fake and we understand that. That said some of our models & actors desire a more frozen look and we can provide these results as well.
There are 43 muscles & 7 nerves in the face and knowing which opposing muscles to inject, which to avoid, how much to inject, which angle to inject at and exactly where in the muscle to inject is the art and science of Aesthetic Injections practiced by Livia Manner, Certified Aesthetic ARNP at [mrktmade_shortcode config=”practice”]. We re-treat patients all the time who went out for a special deal at centers all over South Florida only to find out that all too often that while the price was great, the results sadly were not.
Since 2005, [mrktmade_shortcode config=”practice”] has performed tens of thousands of medical aesthetic treatments and our patients come from all over South Florida and the world. Many newer patients routinely have questions about the history of Botox and its uses and below is a very good article about exactly this topic.
(above written by Brian Sidella of [mrktmade_shortcode config=”practice”])
THE HISTORY & USES OF BOTOX, DYSPORT & XEOMIN
Botulinum toxin is a naturally occurring protein produced by the bacterium clostridium botulinum. This bacterium makes several different types of protein which are called type A to type F. These varying proteins cause muscles to relax at different levels. Botulinum toxin is considered to be the most powerful neurotoxin ever discovered.
Botulinum toxin history goes back almost two hundred years.
In 1822, a German doctor named Justinius Kerner, suggested that botulinum toxin injections might be used in the treatment of excessive sweating or hyperhidrosis. Khalaf Bushara and David Park were the first to show that botulinum toxin injections inhibit sweating (axillary hyperhidrosis). This was the first demonstration of non- muscular use of botulinum toxin. The sweat glands no longer receive the signal to produce sweat. Botox® is now regularly used for this condition.
Researchers discovered in the 1950s that injecting overactive muscles with minute quantities of botulinum toxin type-A would result in decreased muscle activity. This effectively weakens the muscle for a period of three to four months.
In the late 1960s, Botox® was used in American clinics for the treatment of strabismus (crossed eyes) by Alan Scott.
Twenty years later, the real breakthrough came in the wider application of Botox® when Allergan, the American manufacturer of Botox®, was granted approval to market the drug by the Federal Drugs Agency. This gave Allergan the license to sell its new product throughout the U.S. Since then, Botox® has been registered and used in over 90 countries around the world.
The cosmetic effect of BTX-A on wrinkles was originally documented by a plastic surgeon from Sacramento California Dr. Richard Clark.
In 1987 via a Canadian Ophthalmologist, Dr. Jean Carruthers. had been treating her patients who suffered from blepharospasm with Botox®. Dr. Carruthers observed that a “side-effect” of this treatment was the reduction of crow’s feet and wrinkles around the eyes. She then decided to test these findings scientifically together with her husband a dermatologist.
Since then an enormous amount of clinical trial work and patient experience has been established using Botox® for the treatment of wrinkles.
The 3 types of wrinkles: dynamic, static and folds.
Folds are often due to sagging of the underlying facial structures, most notably causing the deep grooves between the nose and mouth known as the naso-labial groove.
Dynamic wrinkles are caused by repeated muscle contraction or facial expressions. The wrinkles appear or worsen through movement and are therefore called dynamic. Some of these wrinkles, like worry lines, frown lines or laugh lines, are often named after facial expressions. When we’re young, our skin is more elastic and the lines easily bounce back to a normal, wrinkle free look. But as we age, these lines become more permanent fixtures in our faces. When the wrinkles are there regardless facial expression, they are called static wrinkles.
Static wrinkles are due to lack of elasticity of the skin caused from sun damage, smoking, genetics, poor nutrition, or from prolonged dynamic wrinkling
If the wrinkle is not caused by muscular contractions, another treatment option such as dermal fillers like Restylane, Juvederm, Radiesse or Belotero should be considered. Fat transfers also offer the longest lasting surgical option as well.
If you’ve even wondered just how many muscles are in your face, the chart on the left will show you. Knowing which opposing muscles to inject, how much to inject and exactly where in the muscle to inject is the art and science of Aesthetic Injections practice at [mrktmade_shortcode config=”practice”].
The most common areas for Botox are:
- Glabellar lines (frown lines)
- Forehead furrows (worry lines)
- Crow’s fee
Other very common cosmetic uses for botulinum toxins are, the treatment of:
- Perioral lines (fine lines around the mouth – also known as smoker lines or lipstick lines or puckering lines)
- Neck bands (platysma bands)
- Eyebrow lift
- Oral commissures also known as marionette- or puppet lines, excessive sweating (hyperhidrosis)
- Bunny lines (on the nose)
- Gummy smile
- “Apple” chin
(not all are registered indications and therewith are off label)
For many years The American Society for Aesthetic Plastic Surgery rated treatment with botulinum toxin the most popular aesthetic procedure in the U.S.
Science has discovered many other clinical uses for botulinum toxin including: wound healing, spasticity in adults and children, strabismus, blepharospasm, incontinence, back pain, achalasia, migraine, acne treatments, dystonia, anal fissure, vocal cord dysfunction, vaginismus, and facial flushing which have all been treated successfully with this important product.
There are currently three different types of botulinum toxin commercially available varieties of type A toxins now FDA approved
Botox® was the first botulinum toxin to gain a cosmetic licence endorsing its use for glabellar lines and wrinkles marketed also under the brand names Vistabel® and Botox® Cosmetic. Botox® is made from purified type – A neurotoxin, manufactured and marketed by Allergan, Inc.
Clostridium botulinum toxin (type) A haemagglutinin neurotoxin complex / purified type – A neurotoxin, has been available as the brand name Dysport®. It gained approval for cosmetic, is manufactured by the French company Ipsen and marketed by Q Med a division of Galderma under the name Azzalure®.
Clostridium botulinum type – A neurotoxin complex. Also known as NT-201, botulinum neurotoxin free from complexing proteins. Manufactured by Merz.